TYPHOLYSIN Meaning and
Definition
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Typholysin is a term used to describe a protein toxin that is produced by the bacterium Clostridium typhoaceticum. This bacterium is commonly known to cause diseases in animals, with a particular affinity for the intestines. Typholysin is regarded as a virulence factor, as it plays a crucial role in the pathogenesis of the bacterium.
The protein toxin is categorized as a hemolysin, which means it has the ability to disrupt and destroy red blood cells. However, it is important to note that typholysin possesses a narrow host specificity, primarily affecting specific animal species. This specificity is manifested in its ability to cause damage to the intestines of its host.
The exact mechanism of action of typholysin is not fully understood, but it is believed to exert its toxic effects by forming pores in the membranes of target cells, disrupting their normal functioning. These pores cause the leakage of important cellular contents, leading to cell death and tissue damage. The presence of typholysin facilitates the bacterium's invasion and colonization of the intestines, ultimately promoting the progression of disease.
Understanding the properties and functions of typholysin is important in studying the pathogenicity of Clostridium typhoaceticum and developing effective strategies for the prevention and treatment of associated diseases.
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An hemolysin formed by Bacillus typhosus.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for TYPHOLYSIN
- typholyrin
- typholysyn
- typholysan
- typholysmn
- typholyshn
- typholysif
- typholysil
- typholysio
- typhoelysin
- typholeysin
- typwhollysin
- t ypholysin
- typh olysin
- typho lysin
- typhol ysin
- typholy sin
- typholys in
- typholysi n
Etymology of TYPHOLYSIN
The word "typholysin" is a combination of two components: "typho-" and "-lysin".
1. "Typho-" is derived from the Greek word "typhos", meaning smoke or mist. In medical terminology, it is commonly used to refer to the typhoid fever caused by the bacterium Salmonella typhi.
2. "-lysin" is a suffix derived from the Greek word "lysis", meaning loosening or dissolution. In biology, "-lysin" is added to the end of a word to indicate a substance or enzyme that causes lysis, which is the breakdown or destruction of cells.
Therefore, "typholysin" can be understood as an enzyme or substance that causes the lysis (breakdown) of cells associated with typhoid fever.
Similar spelling words for TYPHOLYSIN
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